GM Watch
  • Main Menu
    • Home
    • News
      • Newsletter subscription
      • Daily Digest
      • News Reviews
      • News Languages
    • Articles
      • GM Myth Makers
      • GM Reports
      • GM Quotes
      • GM Myths
      • Non-GM successes
      • GM Firms
        • Monsanto: a history
        • Monsanto: resources
        • Bayer: a history
        • Bayer: resources
    • Videos
      • Latest Videos
      • Must see videos
      • Cornell videos
      • Agriculture videos
      • Labeling videos
      • Animals videos
      • Corporations videos
      • Corporate takeover videos
      • Contamination videos
      • Latin America videos
      • India videos
      • Asia videos
      • Food safety videos
      • Songs videos
      • Protests videos
      • Biofuel myths videos
      • Index of GM crops and foods
      • Index of speakers
      • Health Effects
    • Contact
    • About
    • Donations
    • How donations will help us
News and comment on genetically modified foods and their associated pesticides    
  • News
    • Latest News
    • Newsletter subscription
    • News Reviews
    • News Languages
      • Notícias em Português
      • Nieuws in het Nederlands
      • Nachrichten in Deutsch
    • Archive
      • 2021 articles
      • 2020 articles
      • 2019 articles
      • 2018 articles
      • 2017 articles
      • 2016 articles
      • 2015 articles
      • 2014 articles
      • 2013 articles
      • 2012 articles
      • 2011 articles
      • 2010 articles
      • 2009 articles
      • 2008 articles
      • 2007 articles
      • 2006 articles
      • 2005 articles
      • 2004 articles
      • 2003 articles
      • 2002 articles
      • 2001 articles
      • 2000 articles
  • Articles
    • GM Myth Makers
    • GM Reports
    • How donations will help us
    • GM Quotes
    • GM Myths
    • Non-GM successes
    • GM Firms
      • Monsanto: a history
      • Monsanto: resources
      • Bayer: a history
      • Bayer: resources
  • Videos
    • Index of speakers
    • Glyphosate Videos
    • Latest Videos
    • Must see videos
    • Health Effects
    • Cornell videos
    • Agriculture videos
    • Labeling videos
    • Animals videos
    • Corporations videos
    • Corporate takeover videos
    • Contamination videos
    • Latin America videos
    • India videos
    • Asia videos
    • Food safety videos
    • Songs videos
    • Protests videos
    • Biofuel myths videos
    • Index of GM crops and foods
  • Contact
  • About
  • Donations

LATEST NEWS

  • First GMO mosquitoes to be released in the Florida Keys

  • Glyphosate-based herbicide hacks hormones of baby girls after exposure in the womb

  • Pesticides often found in EU foods cause ill health effects missed by regulatory safety tests

  • Researchers call for greater awareness of unintended consequences of CRISPR gene editing

  • Canada Action Alert: Health Canada proposes to remove regulation for some GMOs

GMWatch Facebook cornfield banner

SCIENCE SUPPORTS REGULATION OF GENE EDITING

Plant tissue cultures

GENE EDITING: UNEXPECTED OUTCOMES AND RISKS

Damaged DNA on fire

GENE EDITING MYTHS AND REALITY

A guide through the smokescreen

Gene Editing Myths and Reality

LATEST VIDEOS

  • Seed keepers and truth tellers: From the frontlines of GM agriculture
  • Myths and Truths of Gene-Edited Foods
  • Dangers of gene-edited foods

News Menu

  • Latest News
  • News Reviews
  • Archive
  • Languages

Please support GMWatch

Donations

You can donate via Paypal or credit/debit card.

Some of you have opted to give a regular donation. This is greatly appreciated as it helps place us on a more stable financial basis. Thank you for your support!

Aluminium and glyphosate could act synergistically to cause gut and neurological problems

Details
Published: 18 January 2015
Twitter

New study explains possible mechanisms of action – Claire Robinson reports

Below is the abstract of the latest paper from Stephanie Seneff and co-authors on mechanisms through which glyphosate-based herbicides like Roundup can exercise their toxicity. This paper, co-authored with Nancy Swanson and Chen Li, shows how glyphosate could act synergistically with aluminium to impair gut function and promote neurotoxicity.

As we’ve said before, regulators routinely ignore such information and only move against pesticides based on long-term animal feeding studies. However, even when toxic effects are found, there is a disturbing trend for industry to delay regulatory action based on the fact that no plausible mechanism exists for the toxic effects. This tactic is being used by industry-affiliated authors with regard to glyphosate-based herbicides.

This is in spite of the fact that no law anywhere in the world, as far as we know, mandates the identification of a mechanism of action before pesticide bans can be enacted. And mechanisms have never been precisely identified for some toxic effects of pesticides, such as DDT causing the thinning of birds’ eggshells. However, DDT was nonetheless banned in many countries. The relatively recent preoccupation with plausible mechanisms of action, which regulators play along with, is an unacceptable framing of the debate by industry. It is worrying because whether something is “plausible” to a regulator often has more to do with their belief systems and world view than with what the data actually says.

Seneff and co-authors’ papers on glyphosate and Roundup provide plenty of plausible mechanisms of action. So while we are currently lacking independent animal feeding studies on Roundup using realistic doses to which you and I could be exposed, we are well ahead with regard to mechanistic knowledge. And certainly, people who want to keep themselves and their families healthy can gain valuable information from these papers on what Roundup might be doing to the human body.
—

Aluminum and Glyphosate Can Synergistically Induce Pineal Gland Pathology: Connection to Gut Dysbiosis and Neurological Disease

Seneff, S. , Swanson, N. and Li, C. (2015) . Agricultural Sciences, 6, 42-70. doi: 10.4236/as.2015.61005.
http://www.scirp.org/journal/PaperInformation.aspx?paperID=53106&#.VLqOJ3Z5Lta (open access)

ABSTRACT
Many neurological diseases, including autism, depression, dementia, anxiety disorder and Parkinson’s disease, are associated with abnormal sleep patterns, which are directly linked to pineal gland dysfunction. The pineal gland is highly susceptible to environmental toxicants. Two pervasive substances in modern industrialized nations are aluminum and glyphosate, the active ingredient in the herbicide, Roundup?. In this paper, we show how these two toxicants work synergistically to induce neurological damage. Glyphosate disrupts gut bacteria, leading to an overgrowth of Clostridium difficile. Its toxic product, p-cresol, is linked to autism in both human and mouse models. p-Cresol enhances uptake of aluminum via transferrin. Anemia, a result of both aluminum disruption of heme and impaired heme synthesis by glyphosate, leads to hypoxia, which induces increased pineal gland transferrin synthesis. Premature birth is associated with hypoxic stress and with substantial increased risk to the subsequent development of autism, linking hypoxia to autism. Glyphosate chelates aluminum, allowing ingested aluminum to bypass the gut barrier. This leads to anemia-induced hypoxia, promoting neurotoxicity and damaging the pineal gland. Both glyphosate and aluminum disrupt cytochrome P450 enzymes, which are involved in melatonin metabolism. Furthermore, melatonin is derived from tryptophan, whose synthesis in plants and microbes is blocked by glyphosate. We also demonstrate a plausible role for vitamin D3 dysbiosis in impaired gut function and impaired serotonin synthesis. This paper proposes that impaired sulfate supply to the brain mediates the damage induced by the synergistic action of aluminum and glyphosate on the pineal gland and related midbrain nuclei.

Menu

Home

News

News Archive

News Reviews

Videos

Articles

GM Myth Makers

GM Reports

GM Myths

GM Quotes

How Donations Will Help Us

Contacts

Contact Us

About

Facebook

Twitter

RSS

Content 1999 - 2021 GMWatch.
Web Development By SCS Web Design